Education
- Postdoctoral fellow, National Institutes of Health (NIH/NINDS), 2019 (with Dr. Richard Youle & Dr. Michael Ward)
- Ph.D., Pharmaceutical Sciences, University of Wisconsin-Madison, 2017 (with Prof. Lingjun Li)
- B.S, Chemistry, China Agricultural University; Tsinghua University, 2012 (with Prof. Jinming Lin)
Professional Experience
- Associate Professor, Department of Chemistry & Biochemistry, University of Maryland-College Park, 2024-
- Assistant Professor, Department of Chemistry, George Washington University, 2019-2024
- Assistant Professor (Secondary Appointment), Department of Biochemistry & Molecular Medicine, School of Medicine, George Washington University, 2023-2024
- Editorial Board, Molecular Omics, Royal Society of Chemistry, 2023-
- Advisory Board, US Human Proteome Organization (US-HUPO), 2023-
- Ad hoc reviewer for the National Institutes of Health (NIH) and National Science Foundation (NSF), 2021-
Research Interests
Bioanalytical Chemistry, Mass Spectrometry, Proteomics, Metabolomics, Lipidomics, Neuroscience, Lysosome, Mitochondrion, Disease Biomarker Discovery
Major Recognitions and Honors
- Rising Star in Proteomics and Metabolomics, Journal of Proteome Research, 2024
- Faculty Early Career Award, George Washington University, 2024
- NSF CAREER Award, 2023
- Cottrell Scholar Award, Research Corporation for Science Advancement, 2023
- Young Investigator Award, Chinese American Chromatography Association, 2023
- Inaugural Rising Star Award, Human Proteome Organization (World HUPO), 2022
- Young Investigator Award, Chinese American Society for Mass Spectrometry, 2022
- Emerging Investigator, Journal of the American Society for Mass Spectrometry, 2021
- R.E. Powe Junior Faculty Enhancement Award, Oak Ridge Associated Universities, 2020
- Wisconsin Initiative for Science Literacy Thesis Award, 2017
Research Goals
Quantitative analysis of biomolecules offers a wealth of clues to understand cell biology and disease mechanisms. Mass spectrometry (MS) has become a central technology to study biomolecules. Research in the Hao Lab is focused on developing and applying MS-based bioanalytical chemistry methods, in combination with cell biology and bioinformatics approaches, to study human diseases. Specifically, 1) we develop MS-based methods to study proteins, peptides, metabolites, and lipids in human neurons. 2) we implement multidisciplinary approaches (proteomics, metabolomics, lipidomics, bioinformatics, cell biology, neuroscience, etc.) through collaborative efforts in human stem cell-derived neurons, mouse models, and clinical human subjects to study the lysosomal and mitochondrial dysfunctions of human diseases, particularly brain diseases.
Topics: Bioanalytical Chemistry, Mass Spectrometry, Proteomics, Metabolomics, Lipidomics, Neuroscience, Lysosome, Mitochondrion, Human iPSC-derived Neurons, Disease Biomarker Discovery
We strive to promote a collaborative, inclusive, productive, rigorous, and joyful lab culture.
Check our Twitter page @HaoLabMS and Google Scholar profile.